porcupine bezoar study

Carla Alferes Pinto, Oriente, vol. A study published recently in the journal Global Ecology and Conservation tracked, for the first time, the online trade in old-world porcupines (those from the family Hystricidae in Asia and Africa). Premodern medicine considered bezoars a special kind of stone with antidote properties. Many testimonies have claimed that porcupine dates can effectively cure dengue illness [ 9 ]; however, these claims lack scientific evidence and its relative mechanism of actions is still unknown. The experiment suggests that the best concentration for Porcupine Bezoar Extract (PBE) was at 80.0ug/ml. Porcupine bezoars (phytobezoars) are concretions of undigested plants material that accumulate and calcified in the form of stone within the gastrointestinal tract of porcupine . Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. Porcupine dates are also known as porcupine bezoar, a phytobezoar that is formed from the partly digested plant materials or herbs in the stomach of Himalayan porcupine (Hystrix brachyura) [8, 10]. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. * I speak from my own experience. However, limited scientific study has been carried out to verify these traditional claims. A review on the importance of bezoar has revealed that the oriental bezoars found in monkeys and porcupines (Lapis bezoar orientalis) were considered the most expensive [12–14]. Most listings were from sellers located in Indonesia, followed by sellers from Malaysia, and Singapore. A549 cells morphology was observed after treated with bezoars for 72 hours. This combined method of EP and PBE revealed the process inhibited the proliferation of HeLa cell to 8.48%. Abstract. Porcupine bezoar was found in the gastrointestinal tract of porcupine and made up of indigestible plant matters. The porcupines here eat unpolluted herbs that have high medicinal value causing the bezoars … to be of the rarest and highest value. The price is very high and has collection, medicinal and stockpiling value." However, limited scientific study has been carried out to verify these traditional claims. Porcupine bezoar (PB) is a calcified undigested material generally found in porcupine's (Hystrix brachyura) gastrointestinal tract. Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. The price is very high and has collection, medicinal and stockpiling value”. However, its potential as anticancer agent on human lung cancer cells (A549) is not yet studied. Tannic acid-rich porcupine bezoars induce apoptosis and cell cycle arrest in human colon cancer cells Peng-Nian Yew, Yau-Yan Lim, Wai-Leng Lee Pharmacognosy Magazine 2019 15(65):523-531 Demand for bezoars appears to have increased substantially in recent years. Subscribe to The Revelator’s weekly newsletter. The paper notes that Europeans in the 16th to 19th centuries, who sometimes wore the stones as jewelry, valued porcupine bezoars so much they priced each one “as high as forty times its own weight in gold.”. However, its toxicity profile has never been thoroughly investigated to verify its safety nature. PB is a mass of indigestible foreign material which could be undigested organic or inorganic material that accumulate and conglomerate in the gastrointestinal tract, most commonly in the stomach. However, its potential as an anticancer agent against human cancers is still poorly studied and understood. PB is a type of stone-like substance found in a porcupine's body. The bezoar is traditionally used in South East Asia and Europe for the treatment of cancer, poisoning, dengue, typhoid, etc. While the authors acknowledge the limitations caused by their study’s short time frame and their inability to examine and verify the nature of the bezoars (some of which could have come from other animals or been counterfeits), they still uncovered an alarming level of trade. A porcupine date bezoar is a digestive bezoar, slowly created from a biological mass of ingested food trapped inside the porcupine’s internal digestive tract. Overall, this study demonstrated that PB-A and PB-B possess potential in vitro and in vivo anticancer effects which are elicited through selective cytotoxic effect, induction of apoptosis, inhibition of migration and invasion and anti-angiogenesis. Not only that, it appears to be increasing. Differential diagnosis We monitored e-commerce websites in Singapore, Malaysia, and Indonesia to estimate the extent of porcupine bezoars for sale. © 2020 The Author(s). "Pilot study of temporary controllable gastric pseudobezoars for dynamic non-invasive gastric volume ... Peter, "The Trade, Forgery and Medicinal Use of Porcupine Bezoars in the Early Modern Period (c.1500–1750)", ed. Additionally, porcupine bezoar was also known as lifesaver and used by patients with terminal illness. Bezoars today don’t fetch quite that amount, but the study still found them selling for around $151 a gram — two and a half times the current price of gold — all for a useless clump of congealed, inedible food. Many bezoars are asymptomatic, but some cause symptoms. The experiment suggests that the best concentration for Porcupine Bezoar Extract (PBE) was at 80.0ug/ml. Abstract. However, its potential as an anticancer agent against human cancers is still poorly studied and understood. We use cookies to help provide and enhance our service and tailor content and ads. “The most valuable for the porcupine bezoars are procured from porcupines in the rainforest of Indonesia or Borneo. Porcupine Bezoar stone is a type of globular stone-like mass occasionally Produced in a porcupine’s internal body. The study quotes one popular website: "The most valuable for the porcupine bezoars are procured from … the rainforest of Indonesia or Borneo. Porcupine bezoar (PB) is a calcified undigested material generally found in porcupine's (Hystrix brachyura) gastrointestinal tract. Additionally, porcupine bezoar was also known as lifesaver and used by patients with terminal illness. It was reported as universal medicine in ancient time. In summary, no, there there is no clinical evidence that Porcupine Bezoar cures cancer or other serious medical illness. Until the 18 th century a gold mounted bezoar was included in the crown jewels. The study quotes one popular website: “The most valuable for the porcupine bezoars are procured from … the rainforest of Indonesia or Borneo. Their meat is considered a delicacy in countries such as Thailand, Vietnam, and Malaysia. In present study, porcupine bezoar was tested to observe its ability in inhibiting cell growth of cancer cell (A549) and its cytotoxicity on Normal Human Gingival Fibroblast Cell (HGF-1). Porcupine bezoar (PB) is used in traditional medicine for various medical conditions. Hence, … In present study, porcupine bezoar was tested to observe its ability in inhibiting cell growth of cancer cell (A549) and its cytotoxicity on Normal Human Gingival Fibroblast Cell (HGF-1). Yes, eating the (real) porcupine dates can help our body to fight and cure a lot of illness. Hence, this study … For centuries people have valued these rare “stones” or “dates,” as they’re sometimes called, for their purported healing abilities. 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