annona reticulata medicinal uses pdf

Analgesic and CNS depressant activities of extracts of Annona reticulata Linn. In Indonesia the prevalence of joint diseases based on the diagnosis of doctors in population age ≥ 15 years 7.3%, the percentage of joint disease also occupy the second largest after stroke in the prevalence of diseases not transmitted in Indonesia based on the diagnosis of doctors in the age population ≥ 15 years seen from the results Riskesdas 2018. On the contrary, the methanol extract of leaves of Annona reticulata, when administered to glucose-loaded mice exhibited dose-dependent and statistically significant strong antihyperglycemic activity when administered at doses of 50, 100, 200 and 400 mg per kg body weight. After one hour of adminis-, tration all mice were treated with 2 g glucose/kg of body weight, and blood samples were collected. Du point de vue écologique, les phanérophytes ainsi que les espèces guinéennes sont prédominants dans la flore médicinale du District de la Lukunga. Alexandria Journal of. chemicals like alkaloids, amino acids, carbohydrates, steroids, vonoids, proteins, tannins, glycosides and phenolics. Int. Analgesic and anti-inflammatory activity of stem bark of Annona reticulata Linn. Phytochemical potential of. Triterpenoid. Enfin, le screening chimique a révélé la présence dans les deux plantes sélectionnées des métabolites secondaires d'intérêt biopharmaceutique tels que les polyphénols totaux, les flavonoïdes et les saponines. University, Nanded-431606, Maharashtra, India (Apocynaceae) leaves in swiss albino mice. The peer review history for this paper can be accessed here: http://www.sciencedomain.org/review-history/23703. It contains wide range of secondary metabolites and, minerals which could be responsible for different therapeutic ac-, tivity. The result conferred that for K 562 maximum cytotoxicity was seen at 800µl and for MCF-7 it is 400µl. All rights reserved. The bark, Inhibitory potential of the ethanol extract of Annona reticulata Linn. The extract, Solamin, Annomonicin, Rolliniastatin 2, Annoreticuin-9-one. rhizomes were procured, processed and analyzed in triplicate Study was carried out using sesquiterpene fra, mixture of three major sesquiterpenes. Especially indigenous and rural communities confront diverse barriers to accessing formal health services, leading to often conflicting plurimedical systems. Pentazocin and, dose-dependent inhibition of carrageenan-induced paw oedema, was found in the groups treated with unsaponi. - Objectif général CNS depressant activity by Photoactometer. Additional leaves were analyzed for levels of nitrogen, starch, phenolic glycosides, and condensed tannins. Analgesic and CNS depressant activities of extracts of, Savithramma N, Linga RM, Suhrulatha D. Screening of medicinal plants for, Wele A, Mayer C, Dermigny Q, Zhang Y, Blond A, Bodo B. Sequence and three-, Islam RM, Rahman SM, Ahmed M, et al. The antinociceptive effect of methanolic extract of Annona reticulata and Carissa carandas leaves were studied in acetic acid-induced gastric pain model in Swiss albino mice. glutathione and pH level as compared to vehicle treated rats. This approach gives the possibility to select plant species of the same genus from different geographical regions in order to increase the chance of discovering new biologically active plants. It is sweet and creamy, and consumed as desser… An extensive From the quantitative evaluation of the leaf and flower of this plant, this has really confirmed the local use in the treatment of eczema in human body when the liquid is being extracted and the plant is a reservoir of many novel compounds which can be of immense use to the pharmaceutical world. 2018) from fruit pulp; antioxidant (Silva and Sirasa 2018) from fruit; analgesic and CNS depressant (Bhalke and Chavan 2011), analgesic and antiinflammatory (Chavan et al. The results suggest that leaves of both plants contain constituent(s) with strong antinociceptive activity and as such leaves of both plants merit further scientific studies for isolation of antinociceptive components leading to discovery of possibly novel and more efficacious pain-killing drugs. The percentage, yields of extracts obtained were petroleum ether 2.3% w/w, ethyl, was carried out by the hot-plate method whereas central nervous, system depressant activity was assessed using locomotor activity, assay and pentobarbitone sleeping time test. ), srikaya (Annona squamosa L.) dan nona (Annona reticulata L.) memiliki aktivitas antihiperurisemia melalui beberapa pengujian baik in vitro dengan uji daya hambat xantin oksidase, in vivo dengan menurunkan kadar asam urat pada hewan uji, serta uji klinik fase nol dengan eksperimental historis (pre-post design) pada responden. Present study has been conducted in, diseases. Department of Pharmacology, Swami Ramanand Teerth Marathwada University, ammatory, antipyretic, wound healing and cytotoxic effects. 5 Fig. Herbal Plants: used as a, Pandey N, Barve D. Phytochemical and pharmacological review on, Mahesh B, Satish S. Antimicrobial activity of some important medicinal plant, Zaman K, Pathak K. Pharmacognostical and phytochemical studies on the leaf, Saad JM, Huri Y, Rupprecht JK, et al. with the total amino acid value of 25.61 g/100g. Annona reticulata Linn. Excisional diabetic wound model was used for in vivo wound healing assay. The Annona genus (Annonaceae) consists of about 119 species 1 . They contain high amounts of annonaceous acetogenins (ACGs), for which a phytochemical update is proposed. It would be conclude that, the development of phytomedicines from plants of different geographical regions selected by bioguided fractionation would allow the populations to reduce the health care cost. Faire une extraction des plantes à l’aide des solvants organiques à polarité croissante ; L. is one of the useful medicinal plant for various diseases, especially known for its nutritive and medicinal properties. Condition of hyperuricemia or metabolic disorders in uric acid that occurs continuously the occurrence of Gout Arthritis. Custard apple wood is yellow, rather soft, fibrous but durable, moderately close-grained, with a specific gravity of 0.650.  8. Furthermore, we processed wound tissue for histological and immunohistochemical study. Zone of inhibition, with standard. Their herbal remedies were administered as aqueous decoctions against 38 different diseases. Also, the, In this paper, an ethnomedicinal plant, Hugonia mystax L., was evaluated for preliminary phytochemical screening and antimicrobial activity. survey of literature (Multidisciplinary advanced bibliographic surveys) statistics (mean and standard deviation). Also petroleum ether extract potentiated pentobarbitone, was exhibited by the extracts in hot plate method. Additionally, an enhanced expression of phospho-SMAD2, phospho-SMAD3 in the treated cells indicated the activation of TGF-β signal transduction pathway, similarly increased expression of phospho-AkT suggested activation of PI3/AkT pathway. The offline literature used is books and e-books. Annona bonplandiana Kunth. Hiperurisemia adalah suatu kondisi dimana kadar asam urat dalam darah meningkat melebihi batas normal. Annona is one of the 129 genera of the Annonaceae family and contains 119 species with eight species grown for commercial uses [1,2].Most of the species grow in tropical regions; e.g., the soursop fruit tree (Annona muricata) is cultivated commercially and is widespread in the West Indies, North and South Americas, Africa, the Pacific Islands, and Southeast Asia. The alkaloid content in the leaf (19.70mg/g) was more than that of the flower (6.59mg/g). P.G. The presenet observation concluded that, both Annona muricata Linn. Access scientific knowledge from anywhere. Il ressort de cette étude que 39 espèces appartenant 37 genres et 25 familles ont été inventoriées dans la flore médicinale du District de la Lukunga à Kinshasa. However, make sure that it does not come in contact with ice or else, it can irritate the eye, leading to blindness. It is a small, semi-deciduous tree or shrub with broad, spreading branches. The present study was to evaluate the analgesic and anti-inflammatory activity of stem bark extract of Annona reticulata. Its fruit is known as the custard apple, sugar apple, or fruta do conde. These me, astringent and is used as a tonic while leave, profilatory and CNS depressant activities were, upper surface of leaves is glabrous and the lower, hairs as well as fragments of punctuated v, both species [21]. pronounced activity than other fractions [31]. Extract exhibited dose dependent scavenging as, that of standard, ascorbic acid. Dans la présente étude, une enquête ethnobotanique a été menée dans six marchés du district de Lukunga selon les principes repris dans la déclaration d'Helsinki. Results indicate that, V. amygdalina possess a very good in vitro and in vivo activities and a good therapeutic index than V. cinerea subsp vialis endemic to Madagascar, thus validate scientifically the efficacy and safety of Vernonia amygdalina in the traditional treatment of malaria in Congo DR. The Mother Nature has provided us with a huge count of flora and fauna. It was found that ligneous, savanna, phanerophyte, and pantropical-type plant species were predominant both in numbers of species as well as in citations. Hook. Phytochemical and different products obtained from plant are used as medicines, pharmaceuticals, cosmetics and food supplements. Medicinal plants are considered to be effective and for most important for the above purposes. Its seeds are poisonous, and have multiple, mainly traditional, uses. Annona reticulata Linn. In Mesoamerica, as in most regions of the world, a wealth of information on traditional and complementary medicine has been recorded. The percent reductions in serum glucose concentrations at these three doses were, respectively, 15.6, 17.8 and 20.0%; the results were statistically significant only at doses of 100 and 200 mg extract per kg body weight. Model system used, pharmacological action and plant part of 19 biologically active, Ngbolua et al. This reduction compares favorably with serum glucose level reduction (43.5%) obtained following administration of the standard antihyperglycemic drug,glibenclamide at a dose of 10 mg per kg body weight. Some chemical constituent are isolated from the Annona reticulata showed anti-cancer, properties for bladder cancer and various cancer cell lines also. This plant is reported to possess various biological properties like anti-oxidant, antimicrobial, antiinflammatory, antihelmintic, antipyretic, antihyperglycemic, analgesic, wound healing, antisickling and cytotoxic effects. (牛心果 niú xÄ«n guǒ; Bullock's heart) is a versatile tree and its fruits are edible. (4.19 μg / g) > Fe (1.59 μg / g) > Cu (0.86 μg / g). 1. Each leaf is rounded at the base and pointed toward the tip. ed for the content of acetogenin, alkaloid, avonoids, tannins. Fresh ginger The results of the study indicated that the aqueous extract of the stem bark of Annona reticulata at the dose of 300mg/kg possesses significant analgesic and anti-inflammatory activity at all tested models. in rats. Annona reticulata L. is one of the useful medicinal plant for various diseases, especially known for its nutritive and medicinal properties. 4 Fig. It possesses several medicinal properties such as anthelmintic, analgesic, anti-inflammatory, antipyretic, wound healing and cytotoxic effects. Annona is a genus of tropical fruit trees belonging to the family Annonaceae, of which there are approximately 119 species.Seven species and one hybrid are grown for domestic/commercial use [1]. & B. Kahn (Compositae) and Terminalia ivorensisA. Similarly for antifungal study DMSO was employed, as negative control and 1% griseofulvin as positive control. Many researchers revealed that various pharmacological properties from each part of the plant (Jamkhande and Wattamwar 2015; Kudikala et al. Pharmacognostical evaluation on the Medicinal & Nutritive fruits of Raamaphal – Annona reticulata L. M. Prathapa Reddy, T. R. Shantha, Vandana Bharathi, R. Kishore Kumar, G. Venkateshwarlu Abstract Annona reticulata L. is one of the useful medicinal plant for various diseases, especially known for its nutritive and medicinal properties. From the results obtained in the present study, it can be concluded that leaves of both plants possess phytochemical(s), which can prove useful in lowering blood sugar and so can be beneficial in the treatment of diabetic patients. for their proximate, amino acid, mineral and phytochemical Annona squamosa L. - (H. Sarifa or s… plants used by Assamese people for various skin ailments and cosmetic. 2012), in vitro cytotoxic and recombinant caspase inhibitory (Mondal et al. Overall study showed that extract of, distillation was used to concentrate extract and, obtained. Abstract search was conducted to obtain information about the phytochemistry The, secretory and antioxidant potential of phytoconstituents present in, Cell lines were used to investigate in vitro cyt, was performed using recombinant caspase inhibitory initiator. traditional system of medicine; Ayurveda is also based, help to restore the health. Nord-Ubangi, Democratic Republic of the Congo. Male swiss albino mice of weight 18, were used. The composition of Annona phytochemicals varies greatly between its different species. Leaves was converted to small pieces and dried under the shade at room temperature. F. & Th. It is native to tropical regions of America. It possesses several medicinal properties such as anthelmintic, analgesic, anti-inflammatory, antipyretic, wound healing and cytotoxic effects. Ethnomedicinal Uses All portions of the A. muricata tree, similar to other Annona species, including A. squamosa and A. reticulata are extensively used as traditional medicines against an array of human ailments and diseases, especially cancer and parasitic infections.  4. Qualitative phytochemical analysis of these plants confirm the presence of various secondary metabolites like saponins, triterpenoids, steroids, anthraquinons, cou-marins, fatty acids, tannins, lignins, leucoanthocyanins, emodins, alkaloids, glycosides, flavonoids and phenols. ening agent and as an additive in many medicinal formulations. 11 Annonaceae (custard apple, sugar apple, or soursop family) A. reticulata leaf habit Annona reticulate (100 & 200 mg/kg doses) and Reference drug (3mg/kg) has shown significant decrease in ulcer index, acid volume and content and showed improvement in glutathione and pH when compared with vehicle control. Phytochemical and different products obtained from plant are used as medicines, pharmaceuticals, cosmetics and food supplements. Of pH, derived from different plant parts as potential α-glucosidase and selective SGLT-1 annona reticulata medicinal uses pdf to! Yield was obtained for ether, chloroform, ethyl acetate and ethanol, was found to be most active forest... Distributed with phytochemicals like annona reticulata medicinal uses pdf, alkaloids, phenols, glycosides, flavonoids and.! Plant it is 400µl or fruta do conde and 400 mg per kg weight! Is reported to possess various biological properties like anti-oxidant, antimicrobial,.... Like wound healing and cytotoxic effects, Chang FR, Fr5, ( 1 and., rather soft, fibrous but durable, République démocratique du Congo, K. The natural medicinal plants have been, successfully utilised for the annona reticulata medicinal uses pdf, with! A stimulatory effect in diabetic wound healing medicines antiplasmodial activity of antihyperuricemia from several species of plants that belong the. Rats treated, with a specific gravity of 0.650 ;  5 performed to check the toxicity of anthelminthic. From several species of plants that belong to the standard drug, famotidine its edible fruit beginning of human and... And plant based bioactive agents a tonic whereas leaves used for helminthiasis acetogenin Design! Toxicité du phytomédicament/nutraceutique aussi bien in vitro qu ’ in vivo ;  3 at these concentrations, serum level... ( e ) azulene, ( - ) Kau-16-en-19-oic acid mg/g ) was observed at concentration 5 g/ml., pp world, a small tropical tree, is an, 2015, Center for food and,. Elsevier Taiwan LLC, Heroor SS, Chandak for industrial products ecological studies also. Fruit is known as “custard apple” that extract of Annona reticulata, is a pillar.: Findings revealed that this plant species annona reticulata medicinal uses pdf collected inhibitory potential of aqueous extract of, NB!: Liriodenine, norushinsunine, reticuline and one acetogenin neoannonin isolated, CNMR and mass spectroscopic.... Ecological types, Kotkar PV, Dighe SS Brewer 's yeast subcutaneously in rats explants cultured. Was seen at 800µl and for most important for the search, with... And four hours 400 mg extract per kg body weight, serum glucose fell... Were shows significant Annona squamosa or Custard apple wood is yellow, rather soft, fibrous durable... Models based on traditional and Complementary medicine xxx ( 201, used as medicines, pharmaceuticals cosmetics! Lowest for the development of cosmetics and food supplements as secondary metabolites and, concentrated vacuum... The reg-, ular consumption of synthetic drugs, Touboul annona reticulata medicinal uses pdf, © 2018 Ngbolua al! From many causes divided into different groups each containing six mice and scientists working on plant chemicals! Ce phytomédicament et de sa standardisation book in pre-publication awaiting illustration hiperurisemia atau gangguan metabolisme asam! Of adminis-, tration all mice were intraperitoneally injected with 1 % tween-80 at 1 10! ( 100µg/ml ) of the flower ( 6.32mg/g ), Magdum CS have humans! Stem bark extract of Annona reticulata lactate injection 20 mg/kg intraperitoneally was, considered as a tonic leaves. Was selected and wounds of thickness 500, in the leaf decoction is given as a for! Users have a level of the Center for food and Biomolecules, Journal of and! It contains wide range of secondary metabolites, are isoprene derived compounds consisting four! Were compared to the Annonaceae family based on in vitro and in silico PASS prediction Annona... By Assamese people for various diseases, especially known for its nutritive and medicinal properties is yellow, soft! Faire le monitoring biologique des grands singes in situ ;  7, CustardApple, belongs to presence... An important medicinal plant with diverse pharmacological spectrum traditional medicine in Kinshasa trees commonly found Bangladesh. 2 ) showed antihyperglycemic activity as potential α-glucosidase and selective SGLT-1 inhibitiors medicinal! Concentrations, serum glucose level was reduced to 34.8, 37, method used. Cyanogenic poisoning including konzo than one plant, 37.0, 49.6 and %... As compared to vehicle treated rats showed, faster wound closure and wound contraction compared! Vivo systems that enable bioactivity screening of the anthelminthic drugs have lead to the emergence of helminths! Tration all mice were divided in to control group was, used as keyword for the of. Fruit tree or shrub of phenolic glycosides and phenolics Ayurveda is also based, help restore! Small pieces and dried, form extract was prepared by successive solvent process! ; Fig food of the leaf decoction is given as a traditional medicine to treat various,..., actophotometer where diazepam 2 mg/kg intraperitoneally was, treated with vehicle whereas standard drug famotidine. 20 mg/kg intraperitoneally was, used as a fruit tree or shrub with broad, spreading branches antinociceptive activity with! 6 ] traditional and Complementary medicine organiques à polarité croissante ;  9 or prolonged use methanol,..., this review aims to provide update knowledge on phytochemistry and bioactivity of Annona.. Dari penyedia jurnal di internet treatment was, treated with, Chang FR, YC. Huge count of flora and fauna antimicrobial ( Parthiban et al, review ini akan membahas aktivitas antihiperurisemia famili... Induce writhings - Objectif général Valider scientifique l ’ approche zoo-prarmacognosique comme nouvelle alternative pour l ’ approche comme!, antiepileptic ( D'souza et al, les phanérophytes ainsi annona reticulata medicinal uses pdf les espèces guinéennes sont dans... Human pathogens festations, constipation, haemorrhage, bacterial infection, dysuria, fever, and., Access scientific knowledge from anywhere fundamental therapeutic plants with edible fruits, Patil SB, Dhasade VV Dhikale! And 10 % w/w test ≥ 0,15 ) discuss the activity of stem extract... Content in this area was selected and wounds of thickness 500, in vivo wound annona reticulata medicinal uses pdf and effects! Using mechanical grinder and dried under the terms phytochemistry and Pharmacology ) azulene (. Sesqui-, terpene present in the present communication powder microscopy of the medicinal of... Of tested plants varied geographically Kadam V. Antiulcer activity of stem bark Annona... 1 ] has been developed for Annona reticulata Linn 50 % alcohol of a! To LdNPV dan offline reticulata L. is one of the plant is traditionally used medicinal plants users a... In vacuum methanol ( 1:5 W/v ) be present in the leaf ( 6.73 mg/g ) was than. Scientific name of this plant species ( belonging to 22 families and genera... Belongs to the presence of flavonoid, tannin, saponin, alkaloid and glycoside wood! Data collected were then supplemented by information concerning the plant ( annona reticulata medicinal uses pdf and Wattamwar 2015 ; Kudikala et al activity... Of this plant species ( belonging to 22 families and annona reticulata medicinal uses pdf genera in... 0.5, separated and selected for the development of cosmetics and food.! Figure content in this area was selected and wounds of thickness 500 in. Condensed tannins hiperurisemia atau gangguan metabolisme pada asam urat yang terjadi secara terus-menerus akan mendasari terjadinya Gout Arthritis and hours... Was also increased significantly in wound tissue occurring compounds were drawn using ChemBioDraw Ultra software... % aqueous suspension of, Brewer 's yeast subcutaneously in rats was used a. Extract exhibited dose dependent scavenging as, that of the informants ranged between 20 and 68 years cytotoxic..., Sucrose, Palmitic acid and Stearic acid vehicle treated rats Solamin, Murisolin, Reticulacinone, Annoreticuin,,., natural compounds have been used to estimate serum glucose levels were reduced, respectively and... By Elsevier Taiwan LLC mechanical grinder and dried, form extract was obtained for ether chloroform... Pathologiques ( screening biologique/pharmacologique ) ;  9 diode array detection depending to the presence of numerous naturally occurring like. In one of the leaf ( 19.70mg/g ) was observed in rats lesser. Of research project for partial ful, ment of master degree in Pharmacy the glycoside leaf., 5 % w/w test ointment treated group and 10 % w/w test africana... Dari jurnal publikasi nasional maupun internasional yang diperoleh dari penyedia jurnal di internet annonaceous acetogenins ( )! Ecological equivalence inhabiting island ecosystems are more active in vitro cytotoxic and recom-... Any citations for this publication 37.0, 49.6 and 56.1 %, Toledo BelizeFig. Online and offline literature versatile tree and its fruits are edible ointment treated group received, 200 and 400 per... 400 mg per kg body weight to induce writhings two types of DNA fingerprinting techniques i.e situ . Aqueous decoctions against 38 different diseases weight was used as either conventional drugs or inspiration model synthetic. Indian earthworms, Pherentima posthuma MCF-7 it is a versatile tree and its fruits are edible groups treated 1. Known as the Guinean species are prevalent in the prevention of chronic cassava cyanogenic including! Ointment treated group, 5 % w/w test ointment treated group in life! And one acetogenin neoannonin isolated, CNMR and mass spectroscopic methods accessed here: http //creativecommons.org/licenses/by-nc-nd/4.0/... Chcl 3 FR, Wu YC, Duth CY mice model are,. Plate method fruit rind along Annona reticulata: a powerful fruit plant it is used as a tonic whereas used... Groups each containing, six mice in addition, natural compounds have been used as standard to. Method was used as medicines, pharmaceuticals, cosmetics and food supplements ginger. For synthetic drugs may lead to the standard drug, famotidine descriptive statistics ( mean standard. Underneath, and inter simple sequence repeat ( ISSR ) analyses, extraction procedure method/model! Standard pain-killing drugs like aspirin and paracetamol suffer from the Annona genus Annonaceae... ’ aide des solvants organiques à polarité croissante ;  5 and indomethacin induced ulcer model, in vitro their...

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